Novos Labs – David Sinclar Longevity Supplement Stack
“Based on multiple, recent interviews and his book, Dr. David Sinclair’s supplement and longevity drug stack in 2025 is as follows:
Nicotinamide mononucleotide (NMN): 1g per day, in the morning
Resveratrol: 1g per day, in the morning
Metformin: 800 mg, in the evening
Vitamin D3: ideally 4,000 to 5,000 IU per day
Vitamin K2: ideally 180 to 360 micrograms per day
Statin
Low-dose aspirin: 83 mg per day
Alpha lipoic acid (ALA): recent status unknown
Coenzyme Q10 (coQ10): recent status unknown
Spermidine: 1 mg per day, in the morning
Quercetin and fisetin: 500 mg each, once per day, in the morning
TMG (trimethylglycine or betaine): 500 mg to 1,000 mg per day
Note that Dr. David Sinclair is not affiliated with NOVOS. NOVOS is an independent Public Benefit Corporation with a diverse team of world renowned longevity scientists; this post is an independent analysis of Dr. David Sinclair’s supplementation routine.”
